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婴幼儿围生期是神经系统高速发育的时期,也是脑损伤好发阶段。作为临床最常用的影像学检查方法,头颅磁共振成像(MRI)的变化与疾病进程、年龄、发育和营养等密切相关。现重点从儿童脑发育的阶段性、脑损伤影像学动态变化特点和围生期常见脑损伤的常见病因等角度,探讨婴幼儿围生期脑损伤的头颅MRI影像学临床评估的进展,为围生期脑损伤婴幼儿提供及时合理的早期干预提供影像学基础。“,”In terms of infants, perinatal period is not only a period of the rapid development of nervous system, but also a stage of brain injury.As the most commonly applied imaging method in clinic, the changes of cranial magnetic resonance imaging (MRI) are closely related to disease progression, age, development and nutrition of children.This article presented an overview of the progress of MRI clinical evaluation of perinatal brain injury in infants from the stages of children′s brain development, the dynamic characteristics of imaging changes of brain injury and the common causes of perinatal brain injury, so as to provide imaging basis for timely and reasonable intervention of perinatal brain injury.