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在高血压与心绞痛时,药理学的选择性和β阻断剂的内在拟交感神经活性对临床效用几乎没有影响。然而β阻断剂能推迟低血糖的恢复,对具有低血糖反应倾向的糖尿病患者,是一种具有主要为β_1阻断作用的药物,可能胜过心得安.心得安没有选择性,能推迟胰岛素引起低血糖后的血糖上升,氨酰心安(Atenolol)没有此种作用。醋丁酰心安(Acebutolol)在这方面也比心得安好。有关美多心安(Metoprolol)则意见有分歧;有人发现此药和心得安之间几乎没有差异;又有人观察到此药对血糖浓度没有不良的作用,而心得安能使8例病人中的4例在低血糖发
In hypertension and angina pectoris, the pharmacological selectivity and the intrinsic sympathomimetic activity of the beta blockers have little effect on clinical utility. Beta blockers, however, delay the recovery of hypoglycemia and are a predisposing drug for beta-1 blockers in patients with hypoglycemic predisposing conditions that may outweigh propranolol. Atenolol has no effect on blood sugar after hypoglycemia. Acebutolol is also safer in this respect. There was disagreement about Metoprolol; there was little difference between the drug and propranolol; others observed that the drug had no adverse effect on blood glucose levels and that propofol enabled 4 of 8 patients In low blood sugar hair