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我科新生儿病房从1989年6～12月连续收住从本院婴儿室出院,当天即住我科的腹泻患儿,经1～3次大便培养证实为枸椽酸杆菌感染共27例,从而发现该菌在婴儿室的感染流行。全部病例有不同程度的脱水,绝大部分有酸中毒和低热,大便常规化验大部分正常,13例查药敏均对丁胺卡那敏感。据报告、在新生儿腹泻的病因中,该菌仅次于致病性大肠杆菌及变形杆菌。枸缘酸杆菌为条件致病菌,新生儿特别是应用广谱抗菌素及激素后易发生此类机会性感染,故其病因地位应受到重视。
Our department newborn ward from June 1989 to December continuous admission from hospital discharged from the baby room, that day live in our department of diarrhea in children, after 1 to 3 stool culture confirmed citrate infection in 27 cases, Thus found that the bacteria in the infant room infection prevalence. All cases have different degrees of dehydration, most of the acidosis and fever, stool routine tests most of the normal, 13 cases of drug susceptibility are sensitive to amikacin. It is reported that in the etiology of neonatal diarrhea, the bacteria are second only to pathogenic Escherichia coli and Proteus. Citrobacter is the opportunistic pathogen, neonatal especially after the application of broad-spectrum antibiotics and hormones prone to such opportunistic infections, so its etiological status should be taken seriously.