目前已得到公认的冠心病的主要危险因素有性别、年龄、血脂异常、吸烟、糖尿病等,而低密度脂蛋白(LDL)脂质过氧化是动脉粥样硬化发生过程中的重要环节之一[1]。近年来一系列的生物化学研究结果显示,胆红素能抑制羟过氧化物的产生,被证明是人体内的一种天然抗氧化剂,在生理浓度 Currently, the main risk factors of coronary heart disease have been recognized as gender, age, dyslipidemia, smoking, diabetes, etc. Lipid peroxidation of low density lipoprotein (LDL) is an important link in the development of atherosclerosis [ 1]. In recent years, a series of biochemical studies have shown that bilirubin can inhibit the production of hydroxyperoxides, has proved to be a natural antioxidant in the human body at physiological concentrations