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目的观察小剂量己烯雌酚治疗药物流产后出血的效果。方法当完整绒毛球排出后 ,常规肌注催产素 2 0 IU ,流血仍然较多者行刮宫术 ,对 44例流血不多 (少于月经量 )但 3天内不能止血者 (包括刮宫后的患者 ) ,随机分成两组 ,观察组口服己烯雌酚 0 .2 5 mg,1次 /d,对照组口服云南白药 0 .5 g,3次 /d,血止后 3天停药。两组均用抗生素防治感染。结果 44例均在服药后 8天内止血 ,平均止血时间分别为 (4.6 4± 0 .42 )天 ,(5 .41± 0 .35 )天。3~ 5天血止者分别为 81.82 % ;5 0 .0 0 %。两组比较有显著性差异 (P<0 .0 1;P<0 .0 5 )。无一例发生突破性出血。下次月经恢复及月经量比较无显著性差异 (P<0 .0 5 )。结论当完整绒毛球排出后 ,及时缩宫抗炎 ,再辅以小剂量已烯雌酚口服 ,可有效减少术后出血 ,缩短出血时间
Objective To observe the effect of low-dose diethylstilbestrol in the treatment of bleeding after medical abortion. Methods After the complete villus discharge, conventional intramuscular oxytocin 2 0 IU, bleeding is still more curettage, 44 cases of bleeding less (less than menstrual flow) but can not stop bleeding within 3 days (including patients after curettage ), Were randomly divided into two groups, the observation group oral administration of diethylstilbestrol 0.52mg, 1 / d, the control group oral Yunnan Baiyao 0. 5g, 3 times / d, blood three days after the withdrawal. Both groups were treated with antibiotics to prevent infection. Results All the 44 patients stopped bleeding within 8 days after taking the medication. The average bleeding time was (4.6 4 ± 0.42) days and (5.41 ± 0.35) days respectively. 3 to 5 days of blood were respectively 81.82%; 50.0%. There was significant difference between the two groups (P <0.01; P <0.05). No case of breakthrough bleeding occurred. The next menstrual recovery and menstrual flow no significant difference (P <0. 05). Conclusion When the complete villus discharge, the timely contraction of anti-inflammatory, supplemented with small doses of diethylstilbestrol oral, can effectively reduce the postoperative bleeding and shorten the bleeding time