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很多实验室对妊娠免疫状态研究的主要结论是孕母也能形成直接针对胎儿携带的父性抗原的免疫反应.但与人工移植不同,胎儿引起的同种异体免疫排斥较弱.通常不能达到细胞毒T细胞的程度.另一方面,在孕母体中,尤其是多产小鼠中很易查到起调节和保护作用的成份,即IgG_1增强抗体及抑制性T细胞(Ts),而人工同种异体移植时很少见到上述成份.已如所料,胎盘和胎盘提取物(PE)在这种免疫转向中起一定作用,这些物质已在胎盘细胞、尤其是滋养层细胞上/内表现出来.作者进
The main conclusion from many laboratories on the status of pregnancy immunization is that pregnant mothers also develop an immune response that directly targets the fetus’s parental antigens, but unlike human grafts, the fetus causes less allogeneic immune rejection and usually fails to reach cytotoxicity T cells.On the other hand, it is very easy to find the regulatory and protective components in pregnant maternal, especially in prolific mice, that is, IgG1 -enhanced antibodies and suppressor T cells (Ts), whereas artificial allogeneic The above components are seldom seen when transplanted, and placenta and placenta extract (PE) play a role in this immunosuppression as expected, and these substances have been shown on / in placental cells, especially trophoblast cells. Author into