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致命性的原发性甲状旁腺机能亢进早在1923年就报导了第1例。此后,这样的病例称为急性甲状旁腺中毒、甲状旁腺危象、急性甲状旁腺机能亢进、甲状旁腺激素中毒、钙中毒等。Payne等在一篇甲状旁腺机能亢进危象的论文中认为病人具有以下特征:血清钙增加大于15毫克肠;胃肠道、心血管或中枢神经系统进行性失调;血尿素氮浓度升高或有其他肾功衰竭的证据。著者复习了甲状旁腺危象的94例中只有4例儿童,其中3例因甲状旁腺瘤引起的甲状旁腺危象。第4例病儿因误用大剂量甲状旁腺激素静脉注射6天,当发现后即停止治疗,以后自
Deadly primary hyperparathyroidism as early as 1923 reported the first case. Since then, such cases are called acute parathyroid poisoning, parathyroid crisis, acute hyperparathyroidism, parathyroid hormone poisoning, calcium poisoning. Payne et al. In a paper on the risk of hyperparathyroidism identified the patient as having increased serum calcium greater than 15 mg; progressive disorders of the gastrointestinal, cardiovascular or central nervous system; elevated blood urea nitrogen concentrations or There are other evidence of renal failure. The authors reviewed only 4 of 94 patients with parathyroid crisis and 3 of them had a parathyroid crisis due to parathyroid adenoma. The fourth case of sick children due to misuse of large doses of parathyroid hormone intravenous injection for 6 days, when found to stop treatment, since