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手足口病是由肠道病毒引起的传染病,多发生于婴幼儿,可引起手、足、口腔和臀等部位的疱疹,病程约为4~8天,大部分患者可无明显的临床症状,个别患者可引起心肌炎、肺水肿、无菌性脑膜脑炎等并发症~([1])。手足口病的肠道病毒有20多种(型),柯萨奇病毒A组的16、4、5、9、10型,B组的2、5型,以及肠道病毒71型均为手足口病较常见的病原体,其中以柯萨奇病毒A16型(Cox A16)和肠道病毒71型(EV71)最为常见~([2])。一般仅需对症治疗,预后良好。极少数病例可有脑炎、心肌炎、肺水肿、弛缓性麻痹等并发症,个别危重病人可因多种原因导致死亡[3]。
Hand, foot and mouth disease is caused by enterovirus infection, which occurs in infants and young children, can cause hand, foot, mouth and buttocks and other parts of the herpes, the course of about 4 to 8 days, most patients without obvious clinical symptoms , Individual patients can cause myocarditis, pulmonary edema, aseptic meningoencephalitis and other complications ~ ([1]). Hand, foot and mouth disease enterovirus more than 20 kinds (type), Coxsackievirus A group of 16,4,5,9,10 type, B group of 2,5 type, and enterovirus 71 are hand-foot The most common pathogens are stomatitis, of which Cox A16 and EV71 are the most common ~ ([2]). Generally only symptomatic treatment, the prognosis is good. Very few cases may have encephalitis, myocarditis, pulmonary edema, flaccid paralysis and other complications, some critically ill patients can cause death due to a variety of reasons [3].