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对于老年人,精确地评估肾小球滤过率对明确慢性肾脏病、早期实施保护肾功能的治疗、并给予正确的药物剂量至关重要。临床常用的评估肾功能的方法有血清肌酐、内生肌酐清除率,根据CG公式或MDRD公式估算肾小球滤过率,血清胱抑素C和放射性核素法,还有近年出现的基于血清胱抑素C的估算公式。这些方法在老年人群中的应用各有不足之处。临床需根据实际条件和对诊断精确度的要求,选择合适的方法。
In the elderly, a precise assessment of glomerular filtration rate is crucial for identifying patients with chronic kidney disease, early treatment of renal function, and proper medication dosage. Clinical methods commonly used to evaluate renal function are serum creatinine, endogenous creatinine clearance, according to the CG formula or MDRD formula to estimate glomerular filtration rate, serum cystatin C and radionuclide law, as well as in recent years based on serum Cystatin C estimation formula. These methods have their own weaknesses in the elderly population. Clinical need to be based on the actual conditions and the diagnostic accuracy requirements, choose the appropriate method.