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目的探讨不同程度新生儿缺氧缺血性脑病时血游离钙水平及补充钙剂后的临床转归。方法对血游离钙≤0.9 mmol/L的患儿补充钙剂治疗3 d,观察血游离钙水平和临床状况。结果治疗后患儿血游离钙水平上升,临床抽搐症状减少或消失。结论新生儿缺氧缺血性脑病时病情越重,血游离钙水平越低,补充钙剂有助于缓解临床抽搐症状,稳定病情,从而有助于改善患儿的近期疗效,降低病死率。
Objective To investigate the serum levels of free calcium in neonates with hypoxic-ischemic encephalopathy at different degrees and the clinical outcome after calcium supplementation. Methods Calcium was administered to children with serum free calcium ≤ 0.9 mmol / L for 3 days. The level of serum calcium and clinical status were observed. Results After treatment, blood calcium levels in children increased, the clinical symptoms of tics reduced or disappeared. Conclusions The heavier the condition of hypoxic-ischemic encephalopathy in neonates, the lower the level of free calcium in serum. Calcium supplementation can help relieve the clinical symptoms and stabilize the symptoms of seizures, which can help to improve the short-term curative effect and reduce the mortality.