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目的探讨分析甘精胰岛素联合格列吡嗪治疗2型糖尿病的临床疗效。方法选取2011年1月至2012年2月来我院治疗的2型糖尿病患者140例,随机分为两组,治疗组70例,选用注射甘精胰岛素联合口服格列吡嗪治疗,对照组70例,选用注射诺和灵30R联合口服格列吡嗪治疗,比较两组的临床效果。结果经过治疗,两组全天血糖谱均较基线水平明显下降,下降幅度差异无统计学意义。治疗组的夜间低血糖发生率明显低于对照组,存在显著性差异(P<0.05)。治疗组患者的血糖达标率显著高于对照组(P<0.05)。结论甘精胰岛素联合格列吡嗪治疗2型糖尿病效果显著,值得临床推广应用。
Objective To investigate the clinical efficacy of insulin glargine combined with glipizide in the treatment of type 2 diabetes mellitus. Methods A total of 140 type 2 diabetic patients treated in our hospital from January 2011 to February 2012 were randomly divided into two groups. The treatment group (70 cases) was treated with insulin glargine plus oral glipizide, and the control group 70 For example, the injection of noradren 30R combined with oral glipizide treatment, the clinical effect of the two groups were compared. Results After treatment, the two groups of blood glucose spectrum were significantly lower than baseline levels, the difference was not statistically significant. The incidence of nocturnal hypoglycemia in the treatment group was significantly lower than that in the control group, there was a significant difference (P <0.05). The blood glucose compliance rate of the treatment group was significantly higher than that of the control group (P <0.05). Conclusion Glargine and glipizide are effective in treating type 2 diabetes and are worthy of clinical application.