子宫内膜返流入腹腔,种植、并生长,新的血管建立是逆流内膜种植成活及发展成为子宫内膜异位症(FMs)的关键。血管内皮生长因子(VEGF)是血管形成最关键的因子,异位病灶在腹腔内生长必须有新生血管形成。VEGF与异位病灶活性有关。因此,VEGF在EMs发病中起重要作用。VEGF抗体及其基因治疗阻断异位灶的血管形成有可能成为治疗EMs的重要手段。 Endometrial reflux into the abdominal cavity, planting, and growth, the establishment of new blood vessels is the survival of the reverse flow of endometrial and development of the key to endometriosis (FMs). Vascular endothelial growth factor (VEGF) is the most important factor for angiogenesis. Ectopic lesions must have neovascularization in abdominal cavity. VEGF and ectopic lesions related to activity. Therefore, VEGF plays an important role in the pathogenesis of EMs. VEGF antibody and its gene therapy blocking vascularization of ectopic foci may become an important means of treatment of EMs.