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采用双乳液法研制配糖蛋白B的肠溶微胶囊,考察了微胶囊的形态、粒径及其分布,在摸拟肠液的缓冲液中进行溶解释放试验。配制了两种口服微胶囊混悬制剂,并考察了它的稳定性。
The enteric-coated microcapsules with glycoprotein B were developed by the double emulsion method. The morphology, particle size and distribution of the microcapsules were investigated. The dissolution and release test was carried out in the simulated intestinal fluid buffer. Two oral microcapsule suspension formulations were prepared and investigated for their stability.