目的 :研究肝癌病人肝动脉热化疗栓塞前后 T细胞亚群及 s IL- 2 R的变化及其临床意义。方法 :采用免疫荧光染色法及双抗体夹心法 ,检测 30例原发性肝癌病人治疗前后的 T细胞亚群及 s IL- 2 R的改变 ,并与健康对照组比较分析。结果 :肝癌组治疗前 Th降低 ,Ts和 s IL- 2 R增高 ,与对照组比较有显著差异 ,P<0 .0 1 ,治疗后 Th升高 ,Ts和 s IL- 2 R降低 ,治疗前后比较有显著差异 P<0 .0 1。结论 :检测肝癌病人 T细胞亚群 ,s IL - 2 R的情况 ,有助于了解病人的免疫状况 ,对判断病人预后 ,指导综合治疗有一定价值。热化疗栓塞的疗效优于文献报道的单纯化疗栓塞 Objective: To study the changes and clinical significance of T lymphocyte subsets and sIL-2R before and after hepatic arterial chemoembolization in patients with hepatocellular carcinoma. Methods: Immunofluorescence staining and double-antibody sandwich method were used to detect the changes of T cell subsets and sIL-2R in 30 patients with primary liver cancer before and after treatment, and compared with healthy controls. RESULTS: In the HCC group, Th was decreased before treatment, Ts and sIL-2R were increased, and there was a significant difference compared with the control group. P<0.01, Th increased after treatment, and Ts and sIL-2R decreased before and after treatment. There was a significant difference between P<0.01. Conclusion : The detection of T cell subsets and sIL - 2 R in patients with hepatocellular carcinoma can help to understand the patient’s immune status. It has certain value in judging the patient’s prognosis and guiding comprehensive treatment. The efficacy of thermochemoembolization is superior to that reported in the literature of chemotherapy embolization alone