目的建立气相色谱法测定西地脑中薄荷脑含量的方法。方法在20%PEG-20M色谱柱上,柱温150℃,进样口温度220℃,检测器温度230℃。结果总薄荷脑平均回收率为99.03%,RSD=0.526%;线性范围0.5～2.5mg·mL-1。游离薄荷脑平均回收率为98.44%,RSD=1.829%;线性范围0～0.5mg·mL-1。结论本法简便、快速、准确,可用作西地脑的质量控制。 Objective To establish a gas chromatography method for the determination of menthol in the western brain. Methods On a 20% PEG-20M column, the column temperature was 150 ℃, the inlet temperature was 220 ℃ and the detector temperature was 230 ℃. Results The average total menthol recovery was 99.03% with RSD 0.526% and linear range 0.5-2.5 mg · mL -1. The average recovery of free menthol was 98.44%, RSD = 1.829%. The linear range was 0 ~ 0.5 mg · mL-1. Conclusion This method is simple, rapid and accurate and can be used for quality control of the western brain.