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目的分析临床药师干预临床不合理用药的效果。方法将120例患者随机分为试验组与对照组各60例。对照组采取常规用药管理,试验组在此基础上由临床药师分析医嘱并采取最优化干预方案。评估2组用药不合理情况、住院时间、专项药物费用、抗菌药物费用及用药依从性和不良反应发生情况。结果试验组患者药品用量不当、给药方法不正确、重复用药、专项治疗药品缺失等用药不合理事件发生率均低于对照组,住院时间短于对照组,专项药物费用及抗菌药物费用支出少于对照组,用药依从率高于对照组,不良反应发生率低于对照组,差异均有统计学意义(P<0.05)。结论临床药师应积极参与临床用药指导管理,减少用药不合理情况,积极改善患者用药效果,降低不良反应发生率及病死率。
Objective To analyze the clinical pharmacist intervention clinical irrational effect. Methods 120 patients were randomly divided into experimental group and control group of 60 cases. The control group to take conventional medication management, the experimental group on the basis of clinical pharmacists to analyze the doctor’s advice and take the most appropriate intervention program. Evaluation of two groups of irrational medication, hospital stay, special drug costs, antimicrobial drug costs and drug compliance and adverse reactions. Results In the experimental group, the patients’ illicit drug dosage was improper, the methods of administration were incorrect, the incidences of irrational use of drugs such as repeated medication and special therapeutic drugs were lower than those of the control group, the length of stay was shorter than that of the control group, and the cost of special drugs and antimicrobial drugs were less. In the control group, medication compliance rate was higher than that of the control group, adverse reaction rate was lower than the control group, the difference was statistically significant (P <0.05). Conclusion Clinical pharmacists should actively participate in the guidance of clinical medication management to reduce irrational medication, and actively improve the efficacy of medication in patients, reduce the incidence of adverse reactions and mortality.