克山病是一种病因未明的心肌病。1935年首先在黑龙江省克山县发现。以后,吉林、辽宁、内蒙、陕西、甘肃、山东、山西、河北、河南、四川、云南、湖北等省的部分地区和西藏自治区的少数县陆续报告本病。在国外,目前已知朝鲜北部长白山东麓存在克山病,日本信州地区有过类似疾病的报道。克山病具有地区性、季节性和农业人口多发三大流行特点。我国东北、西北和四川个别病区,过去成年人多发,生育期妇女尤多,近年来以小儿发病为主;山东、云南、湖北和四川多数病区,全部为小儿发病。本病流行时,常呈灶状发病、爆发性发病和转移性发病。克 Keshan disease is a etiology of cardiomyopathy. First discovered in Keshan County, Heilongjiang Province in 1935. Later, the disease was reported one after another in parts of Jilin, Liaoning, Inner Mongolia, Shaanxi, Gansu, Shandong, Shanxi, Hebei, Henan, Sichuan, Yunnan and Hubei provinces and a few counties in the Tibet Autonomous Region. Abroad, it is known that Keshan disease exists in the eastern foot of Changbai Mountain in North Korea and similar diseases have been reported in Shinshu region of Japan. Keshan disease has three major epidemic characteristics of regional, seasonal and agricultural population. In our country, individual wards in northeast, northwest and Sichuan have multiple predispositions in the past and more women in their reproductive years. In recent years, the incidence of these diseases has been mainly in children. Most of the wards in Shandong, Yunnan, Hubei and Sichuan are pediatric cases. The prevalence of this disease, often focal state of onset, the incidence of etiology and metastatic disease. G