作用于α肾上腺素受体的药物,按其立体结构的构型及功能的不同分为α_1和α_2受体两个亚型;按其与受体的亲和性和内在活性可分为激动剂和拮抗剂。本文阐述α_1和α_2受体在效应器上的分布及其功能,从而说明α_1和α_2激动剂与拮抗剂的作用及作用机制,并结合它们的药理作用特性指出今后的趋向。 Drugs acting on the alpha adrenergic receptor are classified into two subtypes of alpha 1 and alpha 2 receptors according to the configuration and function of their stereostructures. According to their affinities and intrinsic activities with the receptors, they can be divided into agonists And antagonists. This article describes the distribution and function of α_1 and α_2 receptors on the effector, indicating the role of α_1 and α_2 agonists and antagonists and their mechanism of action, combined with their pharmacological properties pointed out the future trends.