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本文对有自然流产史的未孕及已孕妇女进行了外周血T淋巴细胞亚群(Tlymphocytesubpopulation,TLS)的检测并对其中8例做了免疫治疗,结果表明:有自然流产史的未孕组较正常未孕组细胞减少(P<0.05);细胞增多(P<0.02),故比值明显降低(P<0.01)。有自然流产史早孕组较正常早孕组间细胞元明显差异,而细胞有明显差异(P<0.05),因此有自然流产史早孕组比值较正常早孕组明显下降(P<0.05)。正常早孕妇女细胞较未孕组减少(P<0.05),细胞无明显变化(P>0.05),因此早孕组比未孕组明显降低(P<0.05)。有自然流产史的未孕组及早孕组细胞无明显差异(P>0.05)。经免疫治疗受孕成功妇女,比值上升,接近于正常早孕组。从实验结果表明,细胞免疫功能失调,是引起流产的原因之一,免疫治疗可以改善自然流产妇女的细胞免疫功能,从而获得成功妊娠。
In this paper, T-cell lymphocyte subsets (TLS) in non-pregnant and pregnant women with history of spontaneous abortion were detected and 8 cases of them were immunized. The results showed that there was no history of spontaneous abortion Compared with normal non-pregnant group, the number of cells decreased (P <0.05); the number of cells increased (P <0.02), so the ratio was significantly lower (P <0.01). The spontaneous abortion history of early pregnancy group compared with the normal early pregnancy group cells were significantly different, and the cells were significantly different (P <0.05), so the rate of spontaneous abortion early pregnancy group than the normal pregnancy group significantly decreased (P <0.05) . Compared with normal pregnant women, the number of normal pregnant women decreased significantly (P <0.05) and the cells did not change significantly (P> 0.05). The history of spontaneous abortion in non-pregnant group and early pregnancy group had no significant difference (P> 0.05). Successful immunization of pregnant women, the ratio increased, close to normal early pregnancy group. From the experimental results show that cellular immune dysfunction is one of the causes of abortion, immunotherapy can improve the spontaneous abortion of women’s cellular immune function, so as to obtain a successful pregnancy.