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对87例丙型肝炎病人的疗效,进行了多因素分析。10例病人行肝穿检查。有血清暴露史者55例,32例无明显的血清暴露史。重叠其它肝炎病毒感染者30例,单纯丙肝病毒感染者57例,平均病史16.12个月。其中12例并发有其它慢性疾病。48例应用α-2b 干扰素治疗1~3个疗程(300万 u/支,每周三次肌注,45支一疗程)。全部病人均采用基本护肝治疗。疗效判定标准分为4级,HCV RNA 持续阴转,谷丙转氨酶(ALT)稳定正常者为持续反应;HCV RNA 暂时阴转和 ALT 迅速恢复正常者为暂时
The efficacy of 87 patients with hepatitis C were analyzed by multivariate analysis. Ten patients underwent liver biopsy. There are 55 cases of history of serum exposure, 32 cases had no history of serum exposure. Overlapped other hepatitis virus infection in 30 cases, 57 cases of simple hepatitis C virus infection, the average history of 16.12 months. Twelve of them complicated with other chronic diseases. 48 cases of treatment with α-2b interferon for 1 to 3 courses (3000000 u / support, intramuscular injection three times a week, 45 a course of treatment). All patients were treated with basic liver protection. The curative effect was divided into 4 grades: HCV RNA persisted negatively and ALT was stable and stable. HCV RNA transiently transient and ALT returned to normal promptly