系统性硬皮病是以皮肤硬化为特征的全身性结缔组织病,其病变为伴有血管障碍的炎性、变性、纤维性改变。病变多侵犯皮肤、滑膜及内脏诸器官,尤以侵犯消化道、心、肾、肺脏为常见。严重者因关节损伤而丧失劳动能力,常由于心、肾受 Systemic scleroderma is a systemic connective tissue disease characterized by skin sclerosis whose lesions are inflammatory, degenerative, fibrotic changes associated with vascular disorders. Lesions and more violations of the skin, synovial and visceral organs, especially violations of the digestive tract, heart, kidney, lung are common. In severe cases due to joint damage and loss of ability to work, often due to heart and kidney affected