本文介绍了美国毒性病理学会(STP)制定并推荐的组织病理学检查内容的标准目录,该目录不受给药途径、实验动物的种系、试验周期、受试药物的种类限制,适用于美国新药注册时的长期毒性试验和致癌试验。并与我国现行的《化学药物长期毒性试验技术指导原则》和《中药、天然药物长期毒性试验技术指导原则》中的相关规定进行比较。 This paper presents a standard list of histopathological tests developed and recommended by the American Society for Toxic Pathology (STP), which is not restricted by the route of administration, the germline of the experimental animal, the duration of the test, the type of drug being tested, Long-term toxicity test and carcinogenicity test when new drug is registered. And compared with the current “Guiding Principles for Long-term Toxicity Test of Chemical Drugs” and “Guiding Principles for Long-term Toxicity Test of Traditional Chinese Medicine and Natural Drugs”.