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继美国普渡大学发现在负碳离子给予一个氢原子的新的电子转移连锁反应后。[J.Org Chem 53,1830(1988)]又发现在团中间体的反应中,一个碳离子有三个电子键,因而引起广泛的注意。[C&EN Dec.7,1987,p32]西密西根大学的Kornblum,Kelly 及陈绍仪(译音)组成了一个研究小组对这项工作进行研究,他们已取得美国国家基金会,Merck 化学公司及石油研究基金会的支持。这项工作的成功有助于难以合成的化合物的制造。例如他们以α苯基丙腈的阴离子与α,β硝基腈反应调入1-硝基二环己基1-碳腈,可得到2,4二苯-2甲基戊二腈,得率为81%及二环己基-1-碳腈,得率为88%,对比之下苯基乙腈阴离子不与硝基腈起反应。
Following the Purdue University found a negative carbon ion to give a hydrogen atom after the new electron transfer chain reaction. [J. Org Chem 53, 1830 (1988)] has also found that in the reaction of the enantiomer, one carbon ion has three electron bonds and therefore attracts a great deal of attention. [C & EN Dec.7, 1987, p32] A team of researchers from Kornblum, Kelly and Chen Shao-yi from the University of Western Michigan studied the work and have already obtained funding from the National Foundation for the United States, Merck Chemicals and Petroleum Research Foundation support. The success of this work contributes to the manufacture of compounds that are difficult to synthesize. For example, they reacted with α, β-nitronitriles and transferred 1-nitrodicyclohexyl-1-carbonitrile with α-phenylpropionitrile anion to obtain 2,4-diphenyl-2methylglutaronitrile 81% and dicyclohexyl-1-carbonitrile, 88% yield, in contrast phenylacetonitrile anion is not reacted with nitronitrile.