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作者研究了~(243),~(244)锔以柠檬酸络合物形式腹腔注射后在 C57BL/DO 小鼠的储留与分布,并将结果与作者们以前所作的的~(239)钚的情形作了比较。实验动物为48只 C57BL/DO 小鼠(10±1周令)按3.5±0.4微居/公斤经腹腔注入溶于 PH=3.5的0.08M 柠檬酸盐溶液中的~(243),~(244)锔。然后籍装有双20×10厘米 NaI(T1)探头的计数仪测定了直至注射后297天的整体小鼠的残余活性。注射后第3、14、56、91和182天每次处死4只小鼠(雌雄各半),立即取出肝脏和双侧股骨,称取湿重。以备有井型NaI(T1)探头的计数仪测定了它们的活性,注射后第14、56和91天每次处死5只小鼠(雄3雌2),将全部骨骼去除肌肉、分别测定双侧股骨和余下骨骼的~(243)锔含量。并将骨骼的活性对股骨活性以最小二乘方法作图。实验结果表明,大部分的锔负荷(>76%)存
The authors studied the retention and distribution of ~ (243) ~ (244) 锔 in C57BL / DO mice after intraperitoneal injection with citric acid complex and compared the results with those of ~ (239) plutonium The situation has been compared. Forty-eight C57BL / DO mice (10 ± 1 week old) were injected intraperitoneally with ~ (243), ~ (244) in 0.08M citrate solution pH = 3.5 at 3.5 ± 0.4 μg / )curium. Then a counter fitted with a double 20x10 cm NaI (T1) probe measures the residual activity of whole mice up to 297 days after injection. Four mice (half male and half female) were sacrificed on days 3, 14, 56, 91 and 182 after injection. Immediately remove the liver and bilateral femurs and weigh the wet weight. Their activity was measured with a counter equipped with a well-type NaI (T1) probe, 5 mice (male 3 female 2) were sacrificed on each of 14, 56 and 91 days after injection, Bilateral femur and the remaining skeletal ~ (243) 锔 content. The activity of the bones is plotted against the activity of the femur using the least square method. Experimental results show that most of the 锔 load (> 76%) deposit