目的探讨负压封闭引流治疗损伤、感染创面的疗效。方法应用负压封闭引流(VSD)治疗损伤感染创面90例。结果 90例体表创面感染均痊愈,创面清洁时间为7~14 d,创面水肿减轻,出现新鲜肉芽组织,细菌培养阴性,其中72例创面愈合,15例植皮愈合,3例二次植皮愈合。结论负压封闭引流治疗体表感染创面,可短期控制感染,促进肉芽生长,使创面愈合,对于皮肤缺损大的病例,为二期植皮手术创造条件。 Objective To investigate the curative effect of negative pressure closed drainage on wounds and wounds. Methods Ninety patients with wounds were treated with vacuum closed drainage (VSD). Results All the wounds in 90 cases were healed. The time of wound cleaning was 7-14 days. The wound edema was relieved. Fresh granulation tissue appeared and the culture of bacteria was negative. Among them, 72 wounds healed, 15 healed skin grafts and 3 healed skin grafts. Conclusion Negative pressure closed drainage treatment of wound surface infection can be short-term infection control and promote the growth of granulation, the wound healing, for the case of large skin defects, to create the conditions for the second stage of skin graft surgery.