论文部分内容阅读
胃复安是一种苯酰胺的衍生物,其结构和普鲁卡因酰胺及舒必利类似。临床以静脉注射该药促进放射检查时胃的排空,并通过口服的方式治疗糖尿病人的胃不全麻痹。该药还用于治疗返流性食道炎、胃潴留、术后肠麻痹、呃逆和直立性低血压。胃复安系促乙酰胆碱释放的多巴胺拮抗剂,它对中枢和外周神经系统都有作用。还能增强胃平滑肌对乙酰胆碱的敏感性。约20
Metoclopramide is a benzamide derivative with a similar structure to procainamide and sulpiride. Clinical intravenous injection of the drug to promote gastric emptying during radiological examination, and oral treatment of gastric incomplete gastric paralysis. This medicine is also used to treat reflux esophagitis, gastric retention, postoperative intestinal paralysis, hiccups and orthostatic hypotension. Metoclopramide is an acetylcholine releasing dopamine antagonist, which has a role in the central and peripheral nervous system. It also enhances the sensitivity of gastric smooth muscle to acetylcholine. About 20