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CA-125是由高分子量糖蛋白组成的抗原,是人体腔上皮的衍生物如卵巢癌上皮提取物,与其相应的抗CA-125抗体(CA-125)是由带有人体卵巢癌抗原的免疫小鼠中产生的一种单克隆抗体。用此单克隆抗体可在多种卵巢癌患者的血清中发现CA-125抗原。但CA-125抗原不仅在卵巢癌患者的血清中发现,还可在多种妇科良性疾患中发现。如子宫内膜异位症患者的血清中CA-125的值也有增加,只是增加的程度低于卵巢癌患者。本文仅就由腹腔镜确诊为子宫内膜异位症或正常盆器者中测量CA-125值并说明其值与疾病程度的关系。作者共研究60例盆区疼痛和不孕症的妇女,由
CA-125 is an antigen composed of high molecular weight glycoproteins and is a derivative of the human luminal epithelium, such as epithelial ovarian epithelial extract. Its corresponding anti-CA-125 antibody (CA-125) is immunized with human ovarian cancer antigen A monoclonal antibody produced in mice. CA-125 antigen can be found in the sera of various ovarian cancer patients using this monoclonal antibody. However, CA-125 antigen is not only found in the serum of patients with ovarian cancer, but also in a variety of gynecological benign conditions. Such as endometriosis serum CA-125 values also increased, but to a lesser degree than in ovarian cancer patients. This article only on laparoscopic diagnosis of endometriosis or normal bowel were measured CA-125 value and explain its value and the extent of the disease. A total of 60 patients with pelvic pain and infertility were studied by the authors