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目的探讨子宫内膜癌患者腹腔细胞学阳性的临床价值,并对其预后的影响进行分析。方法我院于2008年6月份至2012年11月份收治154例子宫内膜癌患者,本组所有子宫内膜癌患者均行手术治疗,且在术中行腹水或腹腔冲洗液细胞学检查。采用Log-rank检验进行单因素分析,Cox回归法多因素分析腹腔细胞学阳性对子宫内膜癌患者的预后影响及其临床价值。结果在154例子宫内膜癌患者中,由42例(27.3%)患者腹腔细胞学检查呈阳性,其中有11例患者在手术后复发死亡,占26.2%。在42例腹腔细胞学阳性的患者中,有12例(28.57%)患者为不良病理类型;有16例(38.10%)患者有深肌层浸润;有11例(26.19%)患者为宫颈受累;有12例(28.57)患者有淋巴结转移。结论腹腔细胞学阳性不能够独立作为检查子宫内膜癌预后的指标。不良病理类型、深肌层浸润、宫颈受累、淋巴结转移是影响腹腔细胞学阳性的高危因素。
Objective To investigate the clinical value of peritoneal cytology in patients with endometrial cancer and to analyze its prognosis. Methods A total of 154 patients with endometrial cancer were treated in our hospital from June 2008 to November 2012. All patients with endometrial cancer underwent surgery in our hospital. Cytological examination of ascites or peritoneal washings during operation was performed. Univariate analysis using Log-rank test and Cox regression analysis were used to analyze the prognosis and clinical value of patients with endometrial cancer who were positive for celiac cytology. RESULTS: Of 154 patients with endometrial cancer, 42 (27.3%) had a positive peritoneal cytology test, and 11 of them died of recurrence after surgery, accounting for 26.2%. Of the 42 patients with positive peritoneal cytology, 12 (28.57%) had poor pathological types; 16 (38.10%) had deep myometrial invasion; 11 (26.19%) had cervical involvement; Twelve patients (28.57) had lymph node metastases. Conclusion The positive results of celiac cytology can not be independently used as an indicator of the prognosis of endometrial cancer. Poor pathological types, deep myometrial invasion, cervical involvement, lymph node metastasis is a risk factor for positive peritoneal cytology.