口服抗生素用于结直肠手术的术前准备,很多文献报道能使术后感染率明显降低。以后有不少研究报道比较了静脉用药与口服用药的效果,意见不一。为此,作者决定进行Nichols和Condon的短期给药方案与作者的一次性静注给药方案的比较观察研究。病人和方法所有住入结直肠组病房的进行择期性手术的病人,随机分为口服新霉素和红霉素组与一次静注灭滴灵和头孢三嗪组,剔除Crohn病、溃疡性结肠炎或憩室病者。所有恶性肿瘤病人都是非梗阻性的。口服药组计29例,其中12例为直肠癌,9例为结肠癌, Oral antibiotics for preoperative colorectal surgery preparation, many reported in the literature can make a significant reduction in postoperative infection. After a lot of research reports comparing the efficacy of intravenous and oral medication, different views. To this end, the authors decided to conduct a comparative study of the short-term dosing regimen of Nichols and Condon with the authors’ one-time intravenous dosing regimen. Patients and Methods All patients undergoing elective surgery in the colorectal ward were randomized to oral neomycin and erythromycin and primary intravenous metronidazole and ceftriaxone to exclude Crohn’s disease and ulcerative colitis Inflammation or diverticular disease. All patients with malignant tumors are non-obstructive. Twenty-nine patients were enrolled in the oral medication group, of which 12 were rectal cancer, 9 were colon cancer,