论文部分内容阅读
背景和目的 尿白蛋白排泄率(AER)水平升高预示发展为终末期肾疾病的高危险性。对链尿霉素诱发的糖尿病予以维生素C或E可减轻白蛋白尿和肾小球肥大。我们试以药理学剂量下维生素C和E来检验其是否能降低伴有高AER的Ⅱ型糖尿病患者的AER。
Background and objective Increased urinary albumin excretion (AER) levels are predictive of high risk of developing end-stage renal disease. Vitamin C or E is given to streptozotocin-induced diabetes to reduce albuminuria and glomerular hypertrophy. We will test whether pharmacological doses of vitamins C and E reduce AER in type 2 diabetic patients with high AER.