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免疫的基本作用是宿主防御,先天性免疫在宿主防御中处于第一线。多细胞生物进化了大量的种系编码受体、模式识别受体(PRRs),能够识别病原体的保守序列。真菌病原体的先天性识别归因于多种PRRs,这些受体可识别真菌细胞壁的多种成分。真菌细胞壁主要由碳水化合物(如β-葡聚糖,甘?
The basic role of immunity is host defense, and innate immunity is at the forefront of host defense. Multicellular organisms have evolved a large number of germline-encoded receptors, pattern recognition receptors (PRRs), that recognize conserved sequences of pathogens. Congenital identification of fungal pathogens is due to a variety of PRRs that recognize multiple components of the fungal cell wall. Fungal cell wall is mainly composed of carbohydrates (such as β-glucan, Gan?