临床使用高渗药物降低眼压,已有六十余年历史。但这些药物各有缺点,例如,降压效果不够理想;药物副作用大;須經靜脉注入,药物配制手續繁瑣等。因此,在应用上受到一定的限制。1961年Virno和Cantore氏用抗水肿药物,指出口服或靜脉注入甘油有明显降低脑水肿之作用。1963年Virao氏曾报告不同类型青光眼26例服甘油降低眼压之效果。近几年来,使用甘油降眼压在 Clinical use of hypertonic drugs to reduce intraocular pressure, more than 60 years of history. However, these drugs have their own shortcomings, for example, antihypertensive effect is not ideal; drug side effects; subject to intravenous injection, drug preparation procedures cumbersome and so on. Therefore, the application is subject to certain restrictions. 1961 Virno and Cantore’s anti-edema drugs, pointed out that oral or intravenous injection of glycerol significantly reduce the role of cerebral edema. In 1963, Virao’s group reported that 26 different types of glaucoma with glycerol to reduce the effect of intraocular pressure. In recent years, the use of glycerin to reduce intraocular pressure in