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本文对50例有不同程度气道阻塞的病员。用放射性示踪微粒测定雾化吸入微粒在肺内沉积的深度和清除率。以观察肺功能、吸入方式对微粒透入肺内的影响。病员在直坐位自口腔吸入单分散的5微米大小微粒(加压),并用同位素~(99)锝标记示踪。每个病员的每次吸气量(V_Ⅰ)用自动活瓣控制,可分为0.11、0.30、0.50、0.76、0.88升5类。44例的气雾平均流率(V)为25.4(13.3～50.4)升/分。雾化时要求每次呼气前迸气8秒钟,雾化完毕立即冲洗口腔,并咽入少量水
In this paper, 50 cases of patients with varying degrees of airway obstruction. The depth and clearance of aerosolized particulates deposited in the lungs were determined using radioactive tracer particles. To observe the lung function, inhalation on the penetration of particles into the lungs. The patient inhaled a monodisperse 5 micron size microparticle (pressurized) from the mouth in a straight sitting position and was labeled with isotope 99 technetium. Each patient’s inhalation volume (V_I) with automatic flap control, can be divided into 0.11,0.30,0.50,0.76,0.88 L 5 categories. The average gas flow rate (V) of 44 cases was 25.4 (13.3 ~ 50.4) l / min. Nebulization required breath before each breath for 8 seconds, spray immediately rinse the mouth, and swallowed a small amount of water