结肠直肠癌肝转移的治疗以肝病灶切除为主,然而不少病人在肝切除后短期内复发死亡,所以有必要找出可预测切除手术获益的指标。 病人和方法:研究者对日本国立医学院医院于1985～1996年收治的85例结肠直肠癌肝转移经治愈性肝切除(同时或异时进行的)病例进行回顾性复习。手术切除范围有肝三段切除、半肝切除乃至转移灶局限性切除不等,但均属治愈性范畴。37例还接受了术后动脉内化疗,平均使用5-氟尿嘧啶6341mg。中位值随访期为52个月(13～118个月)。分析下列有关预后的变量:性别、年龄;原发灶部位(结肠或直肠)、最大直径、分化程度、浸润深度、淋巴结受侵、淋巴管浸润、血管浸润、肿瘤芽生、肠壁内扩散;肝转移灶数目、分布部位(单叶或双叶)、最大直 The treatment of liver metastases of colorectal cancer with hepatic resection based, however, many patients died of recurrence in the short term after liver resection, it is necessary to find out the predictable benefit of resection surgery. Patients and Methods: The researchers retrospectively reviewed 85 patients with liver metastases from colorectal cancer who underwent curative hepatectomy (simultaneous or at different times) admitted to Japan’s National Institutes of Health in 1985-96. Surgical resection range of hepatic resection, hemihepatectomy and even limited removal of metastases range, but are a category of cure. 37 patients also received postoperative arterial chemotherapy, the average use of 5-fluorouracil 6341mg. The median follow-up period was 52 months (range, 13 to 118 months). The following variables related to prognosis were analyzed: gender, age; primary site (colon or rectum), maximum diameter, degree of differentiation, depth of invasion, invasion of lymph nodes, invasion of lymphatic vessels, invasion of blood vessels, tumor budding, The number of metastases, distribution sites (single or double leaves), the largest straight