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我们于1996年应用胸腺肽α_1(Thymosin α1,ZADAXIN,日达仙)治疗抗-HBe、HBV DNA阳性慢性乙型肝炎(慢乙肝)12例,并与同期应用α_1b-干扰素(下称干扰素)治疗的抗-HBe阳性、HBV DNA阳性慢性乙型肝炎15例作对照,所有病例随访3年以观察其长期疗效。现将观察结果报告如下。 1 资料和方法 1.1 研究对象 两组病例为1996年我院传染病科住院和肝病专科门诊病人,诊断均符合1995年第5次传染病与寄生虫
We used thymosin alpha 1 (Thymosin alpha 1, ZADAXIN, Zadaxin) in 1996 to treat anti-HBe and HBV DNA-positive chronic hepatitis B (chronic hepatitis B) in 12 cases. We also used α_1b-interferon (interferon) Anti-HBe treatment positive, HBV DNA positive chronic hepatitis B as control, 15 cases were followed up for 3 years to observe the long-term effect. The observations are reported below. 1 Materials and Methods 1.1 The object of study The two groups of patients in 1996 hospital inpatient infectious diseases and liver specialist outpatients, the diagnosis is in line with the fifth in 1995 infectious diseases and parasites