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目的:探讨急性有机磷农药中毒患者心肌肌钙蛋白-I(cTn-I)的变化。方法:利用化学发光免疫测定法对114例急性有机磷中毒患者cTn-I水平进行测定,并观察患者心脏功能的改变。结果:急性有机磷中毒患者cTn-I水平均有不同程度升高,其升高与中毒程度呈正相关,并随病情缓解呈恢复趋势。结论:急性有机磷中毒患者的病情与cTn-I浓度的变化密切相关,监测急性有机磷农药中毒患者cTn-I的水平有重要的临床意义。
Objective: To investigate the changes of cardiac troponin-I (cTn-I) in patients with acute organophosphorus pesticide poisoning. Methods: The levels of cTn-1 in 114 patients with acute organophosphate poisoning were measured by chemiluminescence immunoassay and the changes of cardiac function were observed. Results: The levels of cTn-I in patients with acute organophosphate poisoning all increased to some extent. The increase was positively correlated with the degree of poisoning and showed a trend of recovery with the severity of illness. Conclusion: The condition of patients with acute organophosphate poisoning is closely related to the change of cTn-I concentration. It is of great clinical significance to monitor the level of cTn-I in patients with acute organophosphorus pesticide poisoning.