论文部分内容阅读
目的探讨大面积烧伤患者血清胱抑素C(Cystatin C,CysC)测定的临床意义。方法检测24例大面积烧伤患者入院及其后10 d内的血清胱抑素C、血清肌酐,并同步测定正常组做比较。结果血清胱抑素C的测定能更明显的反映患者肾功能的变化,且5例发展为肾功能衰竭的患者血清胱抑素C升高提示早于血清肌酐。结论大面积烧伤患者定期检测血清胱抑素C可以动态观察对肾功能的影响及病情的发展。
Objective To investigate the clinical significance of serum cystatin C (CysC) in patients with large area burn. Methods Serum levels of cystatin C and serum creatinine were measured in 24 cases of extensive burn patients admitted to hospital and after 10 days, and compared with the normal group. Results The determination of serum cystatin C could more clearly reflect the changes of renal function in patients, and the elevated serum levels of cystatin C in 5 patients who developed renal failure were earlier than serum creatinine. Conclusion Regular detection of serum cystatin C in patients with extensive burn can be dynamically observed on the renal function and progression of the disease.