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对３组共２０例恶性淋巴瘤病人进行自身外周血干细胞回输，采用三种不同的动员剂和治疗方案：１．皮质激素动员；口服强的松或静注地塞米松可使收集浓聚的白细胞明显增多，为给药前自身血的４．ｂｌ倍和７．２４倍。２．硫酸葡聚糖（ＤＳ）动员：１０％葡萄糖液９～１０ｍｌ＋Ｎ，Ｓ．１００ｍｌ静滴，在外周血干细胞高峰期进行分离，其ＷＢＣ，ＭＮＣ和ＣＦＵ－ＧＭ分别为使用前的２．０４倍、４．１４倍和２．０４倍。３．Ｇ－ＣＳＦ或ＣＴＸ＋Ｇ－ＣＳＦ动员：平均分离２．６次总数可获得ＷＢＣ１５．４７×ｌ０￣９、ＭＮＣ１３．８９×ｌ０￣９、ＣＦＵ－ＧＭ２５．４×ｌ０￣５、１３．２４×ｌ０￣７。临床应用：１．激素动员组化疗采用ＣＴＸ＋ＶＣＲ，分别输入２，１１×１０￣９和２．４０×ｌ０￣９，其中ＣＦＵ－Ｃ产率为０．７２×ｌ０￣５和０．３３×ｌ０￣５，可以加速造血恢复。２．ＤＳ动员组化疗采用ＣＨＶＰ方案，输入自身干细胞ＭＮＣ５．５×ｌ０￣９、ＣＦＵ－ＧＭ１．５４×ｌ０￣５。输后１４天白细胞（ＷＢＣ）恢复至４×ｌ０￣９／Ｌ以上，ＰＴ在输后１６天恢复至照前水平。３．Ｇ－ＣＳＦ或ＣＴＸ＋Ｇ－ＣＳＦ动员组化疗采用ＣＨＶＰ方案或超大剂量化疗（ＢＣＮＵ＋ＶＰ－?
A total of 20 patients with malignant lymphoma in 3 groups were treated with their own peripheral blood stem cells and three different mobilization agents and treatment options were used: 1. Corticosteroids mobilization; Oral prednisone or intravenous dexamethasone can significantly increase the collection of concentrated white blood cells, pre-dose blood 4. Bl times and 7.24 times. 2. Dextran sulfate (DS) mobilization: 10% glucose solution 9 ~ 10ml + N, S. 100 ml of intravenous instillation was performed during the peak period of peripheral blood stem cells. The WBC, MNC and CFU-GM were 2.04, 4.14 and 2.04 times of that before use, respectively. 3. G-CSF or CTX+G-CSF mobilization: The average number of 2.6 isolates is WBC15.47×10-9, MNC13.89×10-9, CFU-GM25.4×10-5, and 13.24×10. 7. Clinical application: 1. The hormone mobilization group received CTX+VCR chemotherapy with 2,11×10 ̄9 and 2.40×10 ̄9, respectively. The CFU-C yield was 0.72×l0 ̄5 and 0.33×l0 ̄5, which accelerated Hematopoietic recovery. 2. In the DS mobilization group, the CHVP protocol was used for chemotherapy and the input stem cells MNC5.5×10-9 and CFU-GM1.54×10-5. White blood cells (WBC) recovered to 4×10 9/L or more after 14 days of transfusion, and PT returned to pre-illumination levels 16 days after transfusion. 3. G-CSF or CTX+G-CSF mobilization chemotherapy with CHVP regimen or large dose chemotherapy (BCNU+VP-?