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目的观察克龄蒙在治疗围绝经期综合征的临床价值及安全性。方法选取我院2012年1月至2013年1月接诊的58例围绝经期综合征患者,对其服用克龄蒙的临床疗效进行观察分析。结果本组患者经过克龄蒙治疗后,K评分、TC、TG和FSH指标明显降低,E2指标及患者子宫内膜厚度明显上升(P均<0.05)。大部分患者的月经紊乱(96.55%)、性欲减退(86.36%)、白带异常(86.54%)、潮热(85.11%)和焦躁(89.74)情况均得到了有效改善。本组共9例不良反应,其中乳房胀痛3例(5.17%)、撤退性出血2例(3.45%)、皮肤瘙痒4例(6.90%),最终均自行消失。结论克龄蒙是一种安全有效的围绝经期综合征治疗药物,能够有效改善患者相关症状,且不良反应可自行消失。
Objective To observe the clinical value and safety of Kelingmeng in treating perimenopausal syndrome. Methods Fifty-eight patients with perimenopausal syndrome who were admitted to our hospital from January 2012 to January 2013 were selected and their clinical efficacy was observed and analyzed. Results After treatment with gram-ling, K scores, TC, TG and FSH were significantly decreased, while E2 and endometrial thickness were significantly increased (all P <0.05). Most patients had significant improvement of menstrual disorders (96.55%), loss of libido (86.36%), abnormal vaginal discharge (86.54%), hot flashes (85.11%) and irritability (89.74). A total of 9 cases of adverse reactions in this group, including breast pain in 3 cases (5.17%), withdrawal bleeding in 2 cases (3.45%), pruritus in 4 cases (6.90%) eventually disappear on their own. Conclusion Kelmung is a safe and effective treatment for perimenopausal syndrome, which can effectively improve the symptoms of patients, and the side effects disappear on their own.