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为探讨自身免疫性甲状腺疾病(AITD)患者的红细胞免疫功能,采用红细胞免疫粘附酵母菌花环法检测正常人40名(对照组)、AITD患者95例(甲亢组52例、甲减组23例及桥本组20例)的红细胞C_3b受体(RBC-C_3bR)花环率及红细胞膜上免疫复合物(RBC-IC)花环率。结果发现3组AITD患者的RBC-IC花环率均高于对照组(均P<0.01),RBC-C_3bR花环率均低于对照组(均P<0.01)。甲亢组RBC-IC与TGA,TMA水平呈正相关(均P<0.05),RBC-C_3bR与TGA、TMA水平呈负相关(P<0.01和P<0.05)。提示AITD患者存在红细胞免疫功能低下.
To investigate the erythrocyte immune function in patients with autoimmune thyroid disease (AITD), 40 healthy subjects (control group) and 95 AITD patients (52 hyperthyroidism patients and 23 hypothyroidism patients) were detected by erythrocyte immunoadsorption yeast wreath method And Hashimoto’s group of 20 cases) of the RBC-C3bR (RBC-C3bR) rosette and erythrocyte membrane immune complex (RBC-IC) rosette rate. The results showed that the RBC-IC rosette rate of three AITD patients was higher than that of the control group (all P <0.01), and the RBC-C 3 RB rosette rate was lower than that of the control group (all P <0.01). There was a positive correlation between RBC-IC and TGA and TMA in hyperthyroidism group (all P <0.05), and RBC-C 3bR was negatively correlated with TGA and TMA levels (P <0.01 and P <0.05). Tip AITD patients with erythrocyte immune dysfunction.