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目的提高抗结核药物对肝脏毒副作用的认识。方法对164例药物性肝炎病人的实验室结果进行回顾性分析。结果抗结核药物引起肝功能不同程度的损伤,损伤程度与患者年龄、性别、用药时间等因素有关。结论抗结核所致药物性肝炎有多种影响因素,应定期检查肝功能,及早发现、及时治疗。
Objective To improve the understanding of toxic and side effects of anti-TB drugs on liver. Methods The laboratory results of 164 patients with drug-induced hepatitis were analyzed retrospectively. Results Anti-TB drugs caused different degrees of liver damage, the degree of injury and patient age, gender, medication time and other factors. Conclusion There are many influencing factors of drug-induced hepatitis due to anti-tuberculosis. Liver function should be checked regularly and detected as soon as possible and treated promptly.