烯氯常见于天然产物中,并被认为是其生物活性官能团之一,在功能材料方面也多有应用,同时也是有机合成中一类重要的合成子。因而,烯氯的制备方法一直是有机合成化学和制药化学的热点研究内容之一。近年来,制备烯氯的新方法和新试剂不断出现,本文基于不同的反应类型,对烯氯的构筑方法进行了综述,并列举了海洋天然产物malyngamides全合成中烯氯应用的重要性。 It is commonly found in natural products and is considered as one of the bioactive functional groups. It is also widely used in functional materials. It is also an important class of synthon in organic synthesis. Therefore, the preparation of alkene has been one of the hot topics in organic synthesis chemistry and pharmaceutical chemistry. In recent years, new methods and new reagents for the production of olefinic chloride are emerging. In this paper, the construction methods of olefinic chloride are reviewed based on different reaction types. The importance of application of olefinic chlorine in the total synthesis of marine natural product malyngamides is also listed.