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将75例急性心肌梗死（AMI）患者分为溶栓再通组（34例）和未溶栓组（41例），观察两组QTc的变化。结果显示：发病后两组的QTc间期均延长，分别为456±48ms、459±51ms，两组比较无显著性差异（P＞0．05），溶栓再通组溶栓治疗后第1、2、4天与未溶栓组比较无显著性差异，而第6、8天两组分别为458±47ms与481±53ms，435±48ms与479±46ms，均出现显著性差异，并且溶栓再通组QTc问期的最大峰值较未溶栓组提前2d出现，同时其再通后的QTc缩短速度较未溶栓组要快。提示溶栓治疗可以改变AMI患者QTc的最大峰值出现时间，而QTc的明显变化对判断溶栓治疗效果可能具有参考意义。
75 AMI patients were divided into thrombolytic group (34 cases) and no thrombolysis group (41 cases), and the changes of QTc in both groups were observed. The results showed that: After the onset of QTc interval between the two groups were extended, respectively 456 ± 48ms, 459 ± 51ms, there was no significant difference between the two groups (P> 0.05), Thrombolysis Thrombolysis after thrombolysis , 2,4 days and no thrombolysis group no significant difference, and the first 6,8 days were 458 ± 47ms and 481 ± 53ms, 435 ± 48ms and 479 ± 46ms, were significant differences, and dissolved The maximum peak value of QTc in the bolt reperfusion group appeared 2 days earlier than that in the non-thrombolytic group, and the QTc shortening speed after the reperfusion was faster than that in the non-thrombolytic group. Tip thrombolytic therapy can change the peak time of QTc AMI patients, and significant changes in QTc may play a reference value for judging the effect of thrombolytic therapy.