帕金森病遗传易患性的研究进展

来源 :中华神经科杂志 | 被引量 : 0次 | 上传用户:CmMocean
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帕金森病 (Parkinsondisease,PD)是一种常见的神经系统变性病 ,病理特征为中脑黑质多巴胺神经元选择性的变性缺失 ,导致其在纹状体投射区的多巴胺减少。PD的病因至今不明。许多年来研究的焦点集中在内外源性神经毒素在其发病中所起的作用。但是 ,近年研究 Parkinson’s disease (Parkinson’s disease, PD) is a common degenerative disease of the nervous system, pathological features of the selective degeneration of dopaminergic neurons in the substantia nigra, resulting in its reduction of dopamine in the striatum projection area. The etiology of PD remains unknown. The focus of many years of research has been on the role of endogenous and exogenous neurotoxins in their pathogenesis. However, recent studies
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