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目的研究连芩解毒颗粒的最佳成型工艺。方法以制粒情况、颗粒形状、溶化性、成型率、吸湿百分率、休止角和口感为评价指标筛选稀释剂、润湿剂和矫味剂的种类和用量,确定最佳成型工艺。结果最佳成型工艺条件为:提取物细粉l份,加入2/3倍稀释剂(糊精-甘露醇=3∶1),加入提取物细粉与稀释剂总量2%的甜菊素调味,混匀,加2%PVPK30的乙醇溶液为润湿剂,制软材,过筛,干燥,整粒,即得。结论连芩解毒颗粒成型工艺可行,颗粒的成型性、抗湿性均良好。
Objective To study the best forming process of Lianqin Jiedu Granules. Methods The optimum forming process was determined by selecting the types and amounts of diluent, wetting agent and flavoring agent based on the evaluation of granulation, particle shape, dissolvability, forming rate, moisture absorption percentage, angle of repose and taste. Results The best forming conditions were as follows: 1 part of extract powder, 2/3 of diluent (dextrin-mannitol = 3: 1), 2% of the total amount of extract powder and diluent , Mix, add 2% ethanol solution of PVPK30 wetting agent, system software, sieved, dried, whole grain, that is, too. Conclusion Lianqin detoxification granules molding process is feasible, the particle shape, moisture resistance are good.