A new biphenyl glycoside along with six known compounds were isolated from the water soluble fraction of the fresh leaves of Eriobotrya japonica. Its structure was elucidated as 5,5′-dihydroxy-3′-methoxybiphenyl-2-O-β-D-glucopyranoside on the basis of cellulase hydrolysis and spectroscopic analysis. A new biphenyl glycoside along with six known compounds were isolated from the water soluble fraction of the fresh leaves of Eriobotrya japonica. Its structure was elucidated as 5,5’-dihydroxy-3’-methoxybiphenyl-2-O-β-D-glucopyranoside on the basis of cellulase hydrolysis and spectroscopic analysis.