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目的:研究床旁单泵血液灌流治疗重度急性有机磷农药中毒(AOPP)的效果。方法:将90例重度急性有机磷农药中毒者随机分为治疗组45例和对照组45例,2组均常规洗胃、导泻、输液及阿托品、氯磷定治疗。治疗组行床旁单泵血液灌流(HP)。结果:治疗组和对照组比较,患者昏迷至清醒时间、阿托品化时间、血清胆碱酯酶活力恢复时间、住院时间明显缩短(P<0.01),阿托品总量明显降低(P<0.01),病死率降低(P<0.05)。结论:HP能迅速清除体内毒物,治疗重度有机磷中毒疗效良好。
Objective: To study the effect of bedside single pump hemoperfusion on severe acute organophosphorus pesticide poisoning (AOPP). Methods: 90 severe acute organophosphorus pesticide poisoning were randomly divided into treatment group (n = 45) and control group (n = 45). Both groups were routinely gastric lavage, catharsis, infusion and atropine and chlorophosphonates treatment. In the treatment group, bedside single pump blood perfusion (HP). Results: Compared with the control group, the time from a patient’s coma to awake, atropisol time, recovery time of serum cholinesterase and hospital stay were significantly shorter (P <0.01), total atropine was significantly lower (P <0.01) Rate decreased (P <0.05). Conclusion: HP can quickly remove the body of toxic substances, the treatment of severe organophosphate poisoning with good effect.