本世纪初Leichtenstern 观察到流感患者常有肌痛,波及腿、背和颈部,流感初期的肌痛发生率高达30～50%,常发生于呼吸道症状之前或同时,肌痛为暂时性,呈良性经过,随流感呼吸道症状缓解而消失。但1957年Lundberg 观察到流感起病3～5天后,于呼吸道症状缓解之际患者突然发生双侧腓肠肌疼痛伴显著触痛的肌病表现。70年代起流感并发肌病的报告增多。目前大多数学者认为除流感早期有暂时性肌痛外,于病程后期可发生急性肌炎或引致横纹肌溶解呈肌红 Early this century, Leichtenstern observed that patients with influenza often have myalgia, which affects the legs, back and neck. The incidence of early onset of myalgia is as high as 30% to 50%, often before or at the same time as respiratory symptoms. Mild pain is temporary After benign, with the relief of respiratory symptoms disappear. However, in 1957, Lundberg observed a sudden onset of bilateral gastrocnemius pain with significant tenderness in patients with respiratory symptoms 3 to 5 days after onset of the flu. There have been reports of flu myopathy since the 1970s. At present, most scholars believe that in addition to the early flu temporary muscular pain, acute myositis may occur in the late course of the disease or cause rhabdomyolysis were red