对真菌茎点霉 2 99的进一步研究 ,又从中分离得到 3个活性化合物 2 99- I、2 99- Y和 2 99- AD。经波谱分析 (UV、EI- MS、1 H- NMR、1 3C- NMR- DEPT、IR) ,证实它们分别与 roridin A、D和 H相同 ,也属于大环内酯 trichothecenes类化合物。 3个化合物均有强的免疫抑制活性 Further studies on the fungal Phyllostachys nobilis 2 99 also isolated 3 active compounds, 2 99-1, 2 99-Y and 2 99-AD. They were also identified as trichothecenes by spectroscopic analysis (UV, EI-MS, 1 H-NMR, 1 3C-NMR-DEPT, IR) All three compounds have strong immunosuppressive activity