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目的探讨使用胰岛素泵皮下输注胰岛素治疗糖尿病酮症酸中毒的临床效果。方法将35例糖尿病酮症酸中毒患者随机分为胰岛素泵治疗组(A组)20例及对照组(B组,小剂量胰岛素持续静脉滴注组)15例。观察两组血糖达标时间,血、尿酮体恢复时间,低血糖人均次数,pH恢复时间。结果胰岛素泵治疗组达到靶血糖时间较对照组短(P<0.05);血pH值恢复正常时间、尿酮体转阴时间及血酮体恢复时间均较对照组显著缩短(P<0.05);发生低血糖人次数低于对照组(P<0.05)。结论使用胰岛素泵输注胰岛素治疗糖尿病酮症酸中毒更加安全有效。
Objective To investigate the clinical effect of subcutaneous infusion of insulin on diabetic ketoacidosis using insulin pump. Methods 35 patients with diabetic ketoacidosis were randomly divided into insulin pump treatment group (A group) 20 cases and control group (B group, low-dose insulin continuous intravenous infusion group) 15 cases. Observe the blood glucose of the two groups compliance time, blood, urine ketone recovery time, the number of low blood sugar per capita, pH recovery time. Results The target blood glucose of the insulin pump therapy group was shorter than that of the control group (P <0.05). The pH value recovery time, urine ketone body negative conversion time and blood ketone body recovery time were significantly shorter than those of the control group (P <0.05) The number of blood sugar people was lower than the control group (P <0.05). Conclusion Insulin pump infusion of insulin for diabetic ketoacidosis is safer and more effective.